Lawrence at Edward Little

Friday, 7 p.m.

Eddies’ run-stuffers will be tested in a challenging opener against the reigning PTC champions, but so will Bulldogs’ secondary.

Lewiston at Mt. Ararat

Friday, 7 p.m.

Chance for the Devils’ explosive young playmakers to shine early against a program that hasn’t won a game since the double-zeroes decade.

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Leavitt at Hampden

Friday, 7 p.m.

It’s a rivalry because the Broncos believe it is, and the early regular-season game is usually more of a battle than the inevitable playoff rematch.

Mt. Blue at Brewer

Friday, 7 p.m.

The Jordan Whitney for Fitzy campaign might as well begin in front of the Penobscot Valley voters.

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Mtn. Valley at Westbrook

Friday, 7 p.m.

Falcons led this one by five touchdowns before the butter cooled on the popcorn a year ago. That probably won’t happen again.

Oxford Hills at Skowhegan

Friday, 7 p.m.

Call this the Night-and-Day Bowl. Vikings go to the flexbone, while Indians adopt spread offense after years of double-wing.

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Greely at Spruce Mountain

Friday, 7 p.m.

Last year’s Rangers couldn’t figure out how to tackle Bill Calden. This year’s Phoenix have their work cut out with Svenn Jacobson.

Falmouth at Gray-NG

Friday, 7 p.m.

Patriots open the Jim Hersom era against a neighboring program that proved you can build one from scratch in Western B.

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Lisbon at Dirigo

Friday, 7 p.m.

Greyhounds won’t have their complete roster yet. Cougars hope to take advantage in what promises to be a crowded Western C playoff race.

Winslow at Poland

Friday, 7 p.m.

Knights begin this season where they ended the previous one. Win over Raiders last October clinched first .500 campaign in school history.

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Winthrop at Sacopee Valley

Friday, 7 p.m.

Long bus ride is probably the biggest obstacle for Ramblers, who still have sour taste from missing playoffs in 2011.

Yarmouth at Oak Hill

Saturday, 1:30 p.m.

Raiders have been Clippers’ victim four times during current win streak, but there’s a new regime and new look on both sides for this one.

Telstar at Traip

Saturday, 1:30 p.m.

Rebels seek first varsity win in more than 30 years against a team expected to challenge for regional and state titles.