Manny Machado went 3 for 5 with three RBIs and Adam Jones had two hits and drove in two for the Orioles, who won on the road for the first time since April 8 and avoided breaking the franchise record for road woes. Baltimore also lost 13 straight on the road while opening the 1988 season 0-21 overall.

Mookie Betts doubled twice and hit his 14th homer for Boston, which lost to Baltimore for the first time in the five meetings so far this season.

Cobb (1-5) got his first win as a member of the Orioles, holding Boston to three runs on 10 hits over 6 1-3 innings. Cobb, who signed with Baltimore as a free agent after spending his first 11 seasons with Tampa Bay, had his longest outing of the season and won for the first time since Sept. 22, when the Rays beat the Orioles.

Brad Brach pitched a scoreless ninth for his sixth save, preserving the Orioles’ first road win since beating the Yankees 8-7 in 12 innings in the 10th game of the season.

Drew Pomeranz (1-2) lasted only four innings for Boston, getting pulled after the Orioles scored four in the fourth to take a 5-1 lead. Pomeranz allowed seven hits and walked three as Baltimore scored five off of him, four of them earned, and struck out a season-low two.

Pomeranz escaped the first trailing 1-0 after loading the bases with one out. He survived the second and third, but couldn’t get himself out of a mess in the fourth after Davis led off with a double and Danny Valencia followed with a single. Pomeranz got the next two batters, but walked Trey Mancini to load the bases for Jones, who delivered a two-run single to left. Machado followed with a line drive single to score two more and put Baltimore up 5-1.

Betts homer to left tied it at 1-all in the third. He also doubled in the fifth as the Red Sox added two more runs to pull within 5-3

After Schoop’s solo shot off of Steven Wright in the seventh put Baltimore up 6-3, the Red Sox got an unearned run and were threatening with the bases loaded before Betts’ pop-out to first ended the rally.

TRAINER’S ROOM

Orioles: RHP Darren O’Day (hyperextended right elbow) threw in bullpen Friday, but manager Buck Showalter said there’s still a little discomfort. “The good news is that it’s structurally fine,” Showalter said. … OF Colby Rasmus (hip) could start a rehab assignment next week, Showalter said.

Red Sox: DH J.D. Martinez returned to the lineup after leaving Thursday’s game in the seventh because of a stomach ailment.

UP NEXT

Orioles: RHP Dylan Bundy (2-5, 4.53 ERA) dropped his ERA by nearly a full run in his last start, throwing seven scoreless innings Sunday while holding Tampa Bay to two hits.

Red Sox: Rick Porcello (5-1, 3.28) has allowed earned five runs in each of his last two starts, taking his first loss of the season Monday against Oakland.